بررسی فراوانی آلودگی به کلامیدیا تراکوماتیس در سقط خودبخودی مراجعه کننده به مراکز درمانی شهید بهشتی به روش Nested PCR در سال 1391

Abstract Background: Bacterial, viral or other infectious pathogens have been regarded as a potential cause of spontaneous abortions during the recent years. This study was done to determine the prevalence of Chlamydia trachomatis infection in women with spontaneous abortion. Materials and methods: This cross-sectional study was performed on women with spontaneous abortions who were referred to Shahid Beheshti University Medical Centers. Samples were taken from the Endocervical area with dacron sterile swabs by Gynecology residents and put in Chlamydia-specific transport medium and transported to the laboratory for Nested PCR DNA. Prevalence and the actual amount of Chlamydia trachomatis was determined. The role of relevant factors was investigated by using K2 tests. Results Of 121 women with spontaneous abortion, 16 patients (2.13%) aged 17 to 38 years were infected with Chlamydia trachomatis. Infection with Chlamydia trachomatis was significantly higher in working women, in those using natural methods of contraception, with increased sexual activity, and with history of previous abortions, (p<0.02). However, no significant relation was found between Chlamydia trachomatis infection and the level of education, history of pregnancy or vaginal discharge. (P <0.3). Conclusion: It seems that in the population studied, the rate of Chlamydia trachomatis infection is similar to the infection rate in neighboring countries but higher than European countries. Keywords: Chlamydia trachomatis, Spontaneous abortion, 2SP medium.