Probable binary fission in a Reed-Sternberg cell.
نویسنده
چکیده
A Reed-Sternberg cell in binary fission was observed in a case of Hodgkin's disease of nodular sclerosis type. This was thought to possibly represent a primitive eukaryotic manifestation or a retrograde replay of the endosymbiotic evolution of the modern eukaryotes as a part of devolution of malignancy (Okuyama and Mishina 1990).
منابع مشابه
Gene expression by single Reed-Sternberg cells: pathways of apoptosis and activation.
Although Hodgkin's disease is highly responsive to treatments that cause apoptosis, it remains resistant to the physiological mechanisms intended to cause cell death. Presumably, the Reed-Sternberg cell defies endogenous apoptosis, persists, accumulates, and manifests the malignant disorder seen clinically. The Reed-Sternberg cell expresses several members of the tumor necrosis factor receptor ...
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ورودعنوان ژورنال:
- The Tohoku journal of experimental medicine
دوره 164 3 شماره
صفحات -
تاریخ انتشار 1991