Treatment of Recalcitrant Pyoderma Gangrenosum with Ulcerative Colitis by Adalimumab Injection
نویسندگان
چکیده
260 Ann Dermatol Received January 21, 2016, Revised May 9, 2016, Accepted for publication May 17, 2016 Corresponding author: Young Lee, Department of Dermatology, Chungnam National University Hospital, 282 Munhwa-ro, Jung-gu, Daejeon 35015, Korea. Tel: 82-42-280-7706, Fax: 82-42-280-7706, E-mail: [email protected] This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/ licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Copyright © The Korean Dermatological Association and The Korean Society for Investigative Dermatology Fig. 1. (A) Initial cutaneous lesion. Five-year history of erythematous, recurrent, painful nodules and ulcers on the left lower leg. (B) Despite several months of treatment, there was only a minimal therapeutic effect. (C) After the 13th injection of etanercept, the pain and ulceration dramatically improved. 4. Kang HY, Kang WH. Guess what! Perforating pilomatricoma resembling keratoacanthoma. Eur J Dermatol 2000;10:63-64. 5. Kost DM, Smart DR, Jones WB, Bain M. A perforating pilomatricomal horn on the arm of an 11-year-old girl. Dermatol Online J 2014;20:22371.
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Biologics for the treatment of pyoderma gangrenosum in ulcerative colitis
Pyoderma gangrenosum (PG) is an uncommon extra-intestinal manifestation of inflammatory bowel disease (IBD). Despite limited published literature, biologics have caused a paradigm shift in the management of this difficult-to-treat skin condition. The clinical data and outcomes of three patients with active ulcerative colitis and concurrent PG treated with biologics (infliximab two and adalimuma...
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