Gradient separation and cytochemical characterisation of neutrophils from kidney of fathead minnow (Pimephales promelas Rafinesque, 1820).

A rapid, direct assay to measure degranulation of primary granules in neutrophils from kidney of fathead minnow (Pimephales promelas Rafinesque, 1820).

A direct, rapid, quantitative colorimetric assay to determine neutrophil primary granule degranulation was adapted for use with fathead minnow kidney neutrophils. The assay measures the exocytosis of myeloperoxidase (MPO) using 3,3',5,5'-tetramethylbenzidine as a substrate. The assay was validated by comparing the total myeloperoxidase content of neutrophil populations obtained from adult cattl...

The Toxicity of the Hydrolysis and Breakdown Products of Malathion to the Fathead Minnow (pimephales Promelas, Rafinesque)*

Abstract Malathion undergoes hydrolysis in aqueous solutions; the products derived from the reaction are dependent upon the pH of the medium. It was the purpose of this investigation to evaluate the toxicity of the products of malathion hydrolysis in the fathead minnow, Pimephales promelas. The studies were conducted by toxicity bioassays of 96 hr duration and continuous exposure tests of 14 da...

EFFECTS OF SERTRALINE EXPOSURE ON FATHEAD MINNOW (Pimephales promelas) STEROIDOGENESIS Dennis R. Carty Thesis Prepared for the Degree of MASTER OF SCIENCE UNIVERSITY OF NORTH TEXAS December 2014 Carty, Dennis R. Effects of Sertraline Exposure on Fathead Minnow (Pimephales

Modeling impacts on populations: fathead minnow (Pimephales promelas) exposure to the endocrine disruptor 17beta-trenbolone as a case study.

Evaluation of population-level impacts is critical to credible ecological risk assessments. In this study, a predictive model was developed to translate changes in fecundity of the fathead minnow (Pimephales promelas) in a short-term laboratory toxicity test to alterations in population growth rate. The model uniquely combines a Leslie population projection matrix and the logistic equation. App...

Histopathology of fathead minnow (Pimephales promelas) exposed to hydroxylated fullerenes

Hydroxylated fullerenes are reported to be very strong antioxidants, acting to quench reactive oxygen species, thus having strong potential for important and widespread applications in innovative therapies for a variety of disease processes. However, their potential for toxicological side effects is still largely controversial and unknown. Effects of hydroxylated fullerenes C60(OH)24 on the fat...