A polydiacetylene-based fluorescent sensor chip.

نویسندگان

  • Jong-Man Kim
  • Young Bok Lee
  • Doo Ho Yang
  • Ji-Seok Lee
  • Gil Sun Lee
  • Dong June Ahn
چکیده

Self-assembled diacetylene vesicles were spotted and immobilized on aldehyde-modified glass substrates using conventional microarray technology. Irradiation of the immobilized diacetylenes allowed generation of nonfluorescent "blue-phase" polydiacetylene (PDA) arrays. Specific interaction of the PDA vesicle arrays with carbohydrates or poly(acrylic acid) solutions afforded fluorescent profiles.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Design of a Fluorescent Sensor Based on the Polydopamine Nanoparticles for Detection of Gallic Acid

Background: Gallic acid (GA) is one of the polyphenolic compounds with antioxidant, antimicrobial and radical scavenging activities, which plays a main role in human health against cancer and cardiovascular diseases. GA concentration can be quantitatively measured in food, medicinal plants and body fluids. Materials and Methods: In this study, MnO2 nanosheets were prepared by reducing potassium...

متن کامل

Biomolecule-Functionalized Smart Polydiacetylene for Biomedical and Environmental Sensing.

Polydiacetylene (PDA) has attracted interest for use as a sensing platform in biomedical, environmental, and chemical engineering applications owing to its capacity for colorimetric and fluorescent transition in response to external stimuli. Many researchers have attempted to develop a tailor-made PDA sensor via conjugation of chemical or biological substances to PDA. Here, we review smart bio-...

متن کامل

Label-free detection of bacterial RNA using polydiacetylene-based biochip.

We developed a simple and effective polydiacetylene-based, label-free multiplex DNA chip for the detection of various pathogenic microorganisms. A novel immobilization method of PDA vesicles on glass slides was exploited using α-cyclodextrin (α-CD). The surface topography of the efficiently immobilized PDA vesicles was confirmed using scanning electron microscopy (SEM) and atomic force microsco...

متن کامل

Responsive Polydiacetylene Vesicles for Biosensing Microorganisms

Polydiacetylene (PDA) inserted in films or in vesicles has received increasing attention due to its property to undergo a blue-to-red colorimetric transition along with a change from non-fluorescent to fluorescent upon application of various stimuli. In this review paper, the principle for the detection of various microorganisms (bacteria, directly detected or detected through the emitted toxin...

متن کامل

New Method for Analysis of image sensor to produce and evaluate the image

In this paper, a new method for evaluating CMOS image sensors based on computer modeling and analysis is introduced. Image sensors are composed of different parts, each of which has a specific effect on image quality. Circuits of image sensors can be evaluated and analyzed using circuit simulators or theoretically, but these methods cannot help to produce the final image. In order to produce th...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Journal of the American Chemical Society

دوره 127 50  شماره 

صفحات  -

تاریخ انتشار 2005