Ammonium salts as an inexpensive and convenient nitrogen source in the Cu-catalyzed amination of aryl halides at room temperature.
نویسندگان
چکیده
Convenient and inexpensive ammonium salts such as NH(4)Cl and aqueous NH(3) solution are found to be readily utilized in the Cu-catalyzed room temperature N-arylation of aryl halides, providing N-unprotected aniline derivatives in high yields.
منابع مشابه
Palladium-Catalyzed Amination of Aryl Chlorides and Bromides with Ammonium Salts
We report the palladium-catalyzed coupling of aryl halides with ammonia and gaseous amines as their ammonium salts. The coupling of aryl chlorides and ortho-substituted aryl bromides with ammonium sulfate forms anilines with higher selectivity for the primary arylamine over the diarylamine than couplings with ammonia in dioxane. The resting state for the reactions of aryl chlorides is different...
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ورودعنوان ژورنال:
- Chemical communications
دوره 26 شماره
صفحات -
تاریخ انتشار 2008