Occurrence and Significance
نویسنده
چکیده
2.1 Monosaccharide Constituents . . . . . . . . . . . . . . . . . . . . . . 2257 2.2 Carbohydrate-Peptide Linkages . . . . . . . . . . . . . . . . . . . . . 2257 2.2.1 N -Glycosides . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2257 2.2.2 O -Glycosides . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2259 2.2.3 GPI Anchors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2260 2.2.4 Uncommon Linkages . . . . . . . . . . . . . . . . . . . . . . . . . . . 2263 2.3 Methods of Glycoprotein Analysis . . . . . . . . . . . . . . . . . . . . 2263 2.3.1 Release of Glycans from Glycoprotein. . . . . . . . . . . . . . . . . . 2264 2.3.2 Labeling and Separation of Glycans . . . . . . . . . . . . . . . . . . . 2264 2.3.3 Sequencing of Glycans . . . . . . . . . . . . . . . . . . . . . . . . . . 2265 2.4 Structure of N -Glycans . . . . . . . . . . . . . . . . . . . . . . . . . . 2265 2.4.1 Diversity of N -Glycans . . . . . . . . . . . . . . . . . . . . . . . . . . 2267 2.4.2 Cell-Type Specific Expression of N -Glycans . . . . . . . . . . . . . . 2269 2.5 Structure of O -Glycans . . . . . . . . . . . . . . . . . . . . . . . . . . 2270 2.5.1 Mucin-Type O -Glycans . . . . . . . . . . . . . . . . . . . . . . . . . . 2271 2.5.2 Non-Mucin O -Glycans. . . . . . . . . . . . . . . . . . . . . . . . . . . 2274 2.6 Proteoglycans. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2276 2.6.1 Carbohydrate-Peptide Linkage Region . . . . . . . . . . . . . . . . . 2276 2.6.2 Structure of Glycosaminoglycans . . . . . . . . . . . . . . . . . . . . 2277
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