Hypothyroidism presenting as Hoffman's syndrome.
نویسندگان
چکیده
Muscle weakness, stiffness and delayed tendon jerk relaxation are usual features of hypothyroidism while muscle hypertrophy, myoedema and wasting are occasionally seen. A 60-year-old male, who presented with proximal muscle weakness and muscle hypertrophy has been reported here. Thyroid function tests, electromyogram and muscle biopsy established the diagnosis of thyroid myopathy with Hoffman's syndrome.
منابع مشابه
Hoffman's syndrome: pseudohypertrophic myopathy as initial manifestation of hypothyroidism. Case report.
The frequency of myopathy in hypothyroidism ranges from 30 to 80%. The major symptoms related are weakness, muscular cramps and myalgia. The pseudohyperthrophic form is called Hoffman's syndrome. The electrophysiological study reveals myopathy, neuropathy or mixed pattern. Laboratorial investigation generally shows increased levels of muscle enzymes and low serum thyroid hormones, with thyrotro...
متن کاملSheehan's syndrome presenting with type III hyperlipoproteinaemia.
A patient is described in whom the presenting feature of hypopituitarism was the development of palmar xanthomata associated with type III hyperlipoproteinaemia. Treatment of her secondary hypothyroidism with thyroxine caused resolution of the xanthomata and hyperlipidaemia, but the underlying compositional abnormality of the lipoproteins could still be observed.
متن کاملThe Clinical Spectrum of Thyrotropin Receptor Gene (TSHR) Mutations
Resistance to thyrotropin (RTSH) is a condition in which thyroid cells show reduced sensitivity to TSH. This condition is characterized by elevated serum TSH concentration, a normal or hypoplastic thyroid gland and normal to very low levels of thyroid hormones. Loss-of-function mutations in the TSH receptor gene (TSHR) lead to RTSH syndrome, presenting with either congenital hypothyroidism (CH)...
متن کاملAmiodarone-Induced Hypothyroidism Presenting as Cardiorenal Syndrome
Here we present the case of a 90-year-old man with chronic heart and renal failure who was admitted with what appeared to be a simple heart failure exacerbation. However, further investigation led to the diagnosis of profound amiodarone-induced hypothyroidism as the cause of his acute decompensation, highlighting the importance of a broad differential diagnosis and thorough investigation.
متن کاملThe Importance of Examining Congenital Hypothyroidism in Connection with Congenital Heart Disease: Letter to Editor
Dear Editor-in-Chief: I read and enjoyed your stylish article, "Frequency of Congenital Cardiac Malformations in Neonates with Congenital Hypothyroidism", in relation to heart disease with hypothyroidism. As we know, one of the most commonly associated congenital hypothyroidism disorders is congenital heart disease, which has a significant effect on the recovery of pat...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Journal of the Indian Medical Association
دوره 102 1 شماره
صفحات -
تاریخ انتشار 2004