Expression of mouse HES-6, a new member of the Hairy/Enhancer of split family of bHLH transcription factors
نویسندگان
چکیده
We studied the expression of mouse HES-6, a new member of the Hairy/Enhancer of split family of basic helix-loop-helix transcription factors. HES-6 is expressed in all neurogenic placodes and their derivatives and in the brain, where it is patterned along both the anteroposterior and dorsoventral axes. HES-6 is also expressed in the trunk, in the dorsal root ganglia and in the myotomes. In the limb buds HES-6 is expressed in skeletal muscle and presumptive tendons.
منابع مشابه
Expression of hes6, a new member of the Hairy/Enhancer-of-split family, in mouse development
Genes of the Hairy/Enhancer-of-split (HES) family encode basic-Helix-Loop-Helix proteins that function as nuclear effectors of Notch signaling to regulate the transcriptional activity of several Notch target genes. Here, we report the characterization of a new member of the HES family, hes6, and describe its expression in mouse embryos ranging from 8.5 to 15.5 dpc. High levels of expression are...
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ورودعنوان ژورنال:
- Mechanisms of Development
دوره 98 شماره
صفحات -
تاریخ انتشار 2000