Muscle Regeneration and Compensatory Growth

Regeneration of skeletal muscle has been documented from an anatomical perspective for a number of years. In recent times the mechanisms that underline skeletal muscle regeneration have been extensively investigated and the topic of a comprehensive edited review by Mauro ( I 979). This brief review wil l focus on cellular proliferation aspects of skeletal muscle regeneration and wil l not attempt to completely cover the large volume of literature in this field. This article wil l deal only with muscle regeneration in mammalian systems which should not be equated with amphibian limb regeneration (Carlson, 1973, 1979).