Alzheimer’s Disease: Molecular Hallmarks and Yeast Models
نویسندگان
چکیده
Abbreviations: Aβ: Amyloid-β Peptide; AD: Alzheimer’s Disease; APP: Amyloid Precursor Protein; ATG: Autophagy-related Protein; Drp1p: Dynamin-Related Protein 1; ER: Endoplasmic Reticulum; ERK: Extracellular signal–Regulated Kinase; HIF: Hypoxia-Inducible Factor; MAM: Mitochondrion-Associated Endoplasmic Reticulum Membrane; MAP: Microtubule Associated Protein; MAPK: MitogenActivated Protein Kinase; Mdivi-1: 3-(2,4-Dichloro-5-methoxyphenyl)2,3-dihydro-2-thioxo-4(1H)-quinazolinone; mtDNA: Mitochondrial DNA; NF-κB: Nuclear Factor Kappa B; PSEN1: Presenilin 1; PSEN2: Presenilin 2; ROS: Reactive Oxygen Species; STAT3: Signal Transducer and Activator of Transcription 3; TNFα: Tumor Necrosis Factor α
منابع مشابه
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8 SAMMANFATTNING 9 ABBREVIATIONS 10 INTRODUCTION 11 Parkinson’s disease 11 Hallmarks of Parkinson’s disease 11 Risk factors 11 Genetic 12 Non-genetic 12 Evaluation of drugs 14 Animal models of Parkinson’s disease 16 Alzheimer’s disease 18 Hallmarks of Alzheimer’s disease 18 Amyloid beta 19 Pathology 21 Astrogliosis in Alzheimer’s disease 22 Risk factors 22 Genetic 23 Non-genetic 25 Evaluation o...
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