Single-molecule DNA detection using a novel SP1 protein nanopore.
نویسندگان
چکیده
SP1 protein as a new type of biological nanopore is described and is utilized to distinguish single-stranded DNA at the single-molecule level. Using the SP1 nanopore to investigate single molecule detection broadens the existing research areas of pore-forming biomaterials from unsymmetrical biological nanopores to symmetrical biological nanopores. This novel nanopore could provide a good candidate for single-molecule detection and characterization of biomaterial applications.
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ورودعنوان ژورنال:
- Chemical communications
دوره 49 17 شماره
صفحات -
تاریخ انتشار 2013