Oral verrucous carcinoma in peninsular Malaysia.

Verrucous carcinoma is a form of squamous cell carcinoma which was first described as a distinct clinical and pathological entz'ty by Ackerman iri 1948. This study is the [irst report of 44 cases in Malaysians. Verrucous Carcinoma (VC) formed 1.8 percent of all oral squamous cell carcinoma cases. There was a predominance ofmales (M:F = 1.4:1). The peak age incidence was between 51 70 years (66 percent). The buccal mucosa (43 percent), gingioae (20 percent) and commissures of lzps (17 percent) were the commonest sites of inooloement, The Chinese who do not chew the betel quid had the least frequency of vc. No case was reported in the Chinese female. The highest frequency of vc was in. the Indians who often added tobacco to their betel quids. Although thz'rty three years have passed since A ckerman 's first description of vc it still remains a mystery. Clinicians, pathologists and immunologists z'n Southeast Asia have the opportunz'ty to study and contribute to a better