Is computed tomographic angiography prognostic in patients with cardiac symptoms?

e welcome the interest of Drs. Rapezzi and colleagues in our rticle (1). We did not discuss radionuclide imaging of amyloid ith tracers developed for bone scintigraphy because few data are vailable and because of constraints of space. Bone scintigraphy in myloidosis has been evaluated systematically only in very small eries (2), and there is no evidence as yet for a specific molecular nteraction between bone-seeking isotopes and amyloid deposits. e believe that the suggestions by Dr. Rapezzi and colleagues that one scintigraphy can facilitate the differential diagnosis of ransthyretin and AL cardiac amyloidosis is therefore unsubstaniated in light of present knowledge but that further investigation f this interesting phenomenon is warranted.