Influence of Imprecision on ROC Curve Analysis for Cardiac
نویسندگان
چکیده
Influence of Imprecision on ROC Curve Analysis for Cardiac Markers, Peter Kupchak, Alan H.B. Wu, Farooq Ghani, L. Kristen Newby, E. Magnus Ohman, and Robert H. Christenson ( Nanogen, Point of Care Diagnostics Division, Toronto, Ontario, Canada; 2 Department of Laboratory Medicine, San Francisco General Hospital/University of California, San Francisco, CA; 3 Bayer Healthcare Corporation, Tarrytown, NY; 4 Department of Medicine, Division of Cardiology, Duke University Medical Center, Durham, NC; 5 Department of Pathology, University of Maryland Medical Center, Baltimore, MD; * address correspondence to this author at: Department of Laboratory Medicine, San Francisco General Hospital, 1001 Potrero Ave., San Francisco, CA 94110; fax 415-206-3045, e-mail [email protected])
منابع مشابه
Influence of imprecision on ROC curve analysis for cardiac markers.
BACKGROUND There has been considerable debate regarding the impact of assay imprecision on the performance of cardiac biomarkers for diagnosis of acute coronary syndromes (ACS) and risk stratification for future adverse cardiac events. METHODS Using existing data from 2 published clinical trials, we used a resampling method to statistically introduce 5%, 10%, and 20% imprecision to results fo...
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