Effect of triiodothyronine (T3) excess on fatty acid metabolism in the soleus muscle from endurance-trained rats.Effect of triiodothyronine (T3) excess on fatty acid metabolism in the soleus muscle from endurance-trained rats
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چکیده
Complete List of Authors: Górecka, Monika; Mossakowski Medical Research Centre, Department of Applied Physiology Synak, Marcin; Mossakowski Medical Research Centre, Department of Applied Physiology Brzezińska, Zofia; Mossakowski Medical Research Centre, Department of Applied Physiology Dąbrowski, Jan; Mossakowski Medical Research Centre, Department of Applied Physiology Zernicka, Ewa; Mossakowski Medical Research Centre, Department of Applied Physiology
منابع مشابه
The Effect of a 6-week Endurance Training on BDNF and TrKB Gene Expression in the Soleus of Rats with Diabetic Neuropathy
Background & Aims: Diabetic neuropathy can lead to atrophy and weakness of distally located muscles and lack of neurotrophic support is believed to contribute to the development of these consequences. So, the aim of the present study was to investigate BDNF and TrKB gene expression in soleus muscle of Wistar male rats with diabetic neuropathy following endurance training....
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Stearoyl-CoA desaturase (SCD), a rate-limiting enzyme in the biosynthesis of monounsaturated fatty acids, has recently been shown to be a critical control point in regulation of liver and skeletal muscle metabolism. Herein, we demonstrate that endurance training significantly increases both SCD1 mRNA and protein levels in the soleus muscle, whereas it does not affect SCD1 expression in the EDL ...
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Background and Objectives: Oxidative stress from exercise, either injured muscles and reduces performance in athletes, or stimulates the production of cytokines from many cells. body respond to oxidative stress by activating antioxidant defenses and other protective devices to counteract these body pressures. Therefore, the purpose of this study is to investigate the effect of 8 weeks of stren...
متن کاملEndurance training increases FFA oxidation and reduces triacylglycerol utilization in contracting rat soleus.
We examined the effects of 8 wk of intense endurance training on free fatty acid (FFA) transporters and metabolism in resting and contracting soleus muscle using pulse-chase procedures. Endurance training increased maximal citrate synthase activity in red muscles (+54 to +91%; P </= 0.05) but failed to increase cytosolic fatty acid binding protein content, mRNA for fatty acyl-CoA synthase, and ...
متن کاملEndurance training partially reverses dietary-induced leptin resistance in rodent skeletal muscle.
Leptin acutely stimulates skeletal muscle fatty acid (FA) metabolism in lean rodents and humans. This stimulatory effect is eliminated following the feeding of high-fat diets in rodents as well as in obese humans. The mechanism(s) responsible for the development of skeletal muscle leptin resistance is unknown; however, a role for increased suppressor of cytokine signaling-3 (SOCS3) inhibition o...
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تاریخ انتشار 2015