Tissue specificity of Caenorhabditis elegans enhanced RNA interference mutants.
نویسندگان
چکیده
Gene knockdown by RNA interference (RNAi) in Caenorhabditis elegans is readily achieved by feeding bacteria expressing double-stranded RNA (dsRNA). Enhanced RNAi (Eri) mutants facilitate RNAi due to their hypersensitivity to dsRNA. Here, we compare eight Eri mutants for sensitivity to ingested dsRNA, targeting a variety of tissue-specific genes.
منابع مشابه
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ورودعنوان ژورنال:
- Genetics
دوره 188 1 شماره
صفحات -
تاریخ انتشار 2011