Allergenarrays: low-cost food allergy diagnosis using allergen extracts-based microarrays
نویسندگان
چکیده
Background The current tools available for diagnosing food allergy include the clinical history, trial elimination diets, diet diaries, skin prick testing (SPT) and allergen-specific serum IgE testing. Since 15 years, development of allergen-based microarrays using recombinant/natural proteins is increasing, resulting in commercially available microarrays to detect specific IgE against more than 100 allergenic compounds. For the moment, the number of available recombinant allergens and the cost of their development limit the enhancement of allergen microarray technology. The goal of our study is to explore and optimize allergen-microarray from food allergen extracts and trying to create a low-cost IgE detecting platform.
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