HPV vaccines in immunocompromised women and men
نویسندگان
چکیده
HIV-positive as well as other immunocompromised women and men have increased risk of human papillomavirus (HPV)-associated nogenital and oral cancers. The effectiveness of a HPV vaccine to reduce the incidence of these tumors in immunocompromised individuals ay depend on several factors, including the effects of immunocompromise on the response to vaccination, the extent of prior infection ith the HPV types included in the vaccine, whether immunocompromised women and men have tumors that contain types of HPV not n the vaccines more often than the general population, and whether or not immunization occurs before immunocompromise is severe. linical studies are needed to determine HPV vaccine safety and effectiveness in different populations of immunocompromised women nd men. 2006 Elsevier Ltd. All rights reserved.
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Human papillomavirus vaccination: recommendations of the Advisory Committee on Immunization Practices (ACIP).
This report summarizes the epidemiology of human papillomavirus (HPV) and associated diseases, describes the licensed HPV vaccines, provides updated data from clinical trials and postlicensure safety studies, and compiles recommendations from CDC's Advisory Committee on Immunization Practices (ACIP) for use of HPV vaccines. Persistent infection with oncogenic HPV types can cause cervical cancer...
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