Two New Flavonol Glycosides from Polygala sibirica L. var megalopha Fr.

نویسندگان

  • Yan-Jie Huang
  • Ling-Yun Zhou
  • Jun-Min Wang
  • Qiang Li
  • Yuan-Yuan Geng
  • Hai-Yang Liu
  • Yan Hua
چکیده

Two new flavonol glycosides, named polygalin H (1) and polygalin I (2), as well as the known compound polygalin D (3), were isolated from the whole plant of Polygala sibirica L. var megalopha Fr. Their structures were elucidated on the basis of spectroscopic data analysis. These flavonol glycosides exhibited strong inhibitory activities against xanthine oxidase in vitro. Their half-maximal inhibitory concentrations (IC50) were calculated, which were 9.48, 8.31, 16.00 μM, respectively.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Two new flavonol glycosides from Sarcopyramis bodinieri var. delicate.

Detailed chemical investigation of the herb Sarcopyramis bodinieri var. delicate resulted in the isolation of two new flavonol glycosides, namely, isorhamnetin-3-O-(6''-OE-feruloyl)-beta-D-glucopyranoside (1) and isorhamnetin-3-O-(6''-O-E-feruloyl)-beta-Dgalactopyranoside (2). In addition, four known compounds, quercetin-3-O-(6''-acetyl)-beta-Dglucopyranoside (3), isorhamnetin-3-O-(6''-acetyl)-...

متن کامل

Flavonol Glycosides from Paederia scandens

Four kaempferol glycosides and five quercetin glycosides have been isolated from a methanolic extract of Paederia scandens var. mairei leaves and stems, in which in addition four un­ known glycosides of kaempferol and quercetin are present in a trace. Nine flavonol glycosides including a new glycoside quercetin 3-0-rutinoside-7-0-xylosylglucoside (paederinin) were identified by PC, HPLC, UV spe...

متن کامل

Isolation and Identification of Flavonol Glycosides from Lathyrus Armenus (Boiss. & Huet)

In the last five decades study on plant secondary metabolites have been increasing. Higher plants with a wide range of secondary metabolites have been very important in the search of new therapeutic agents. Flavonoids are most widely distributed secondary natural metabolites that found in plants which occuring in free forms or as glycosides with polyphenolic structure. In this study secondary m...

متن کامل

Isolation and Identification of Flavonol Glycosides from Lathyrus Armenus (Boiss. & Huet)

In the last five decades study on plant secondary metabolites have been increasing. Higher plants with a wide range of secondary metabolites have been very important in the search of new therapeutic agents. Flavonoids are most widely distributed secondary natural metabolites that found in plants which occuring in free forms or as glycosides with polyphenolic structure. In this study secondary m...

متن کامل

Genetic Variation of Flavonols Quercetin, Myricetin, and Kaempferol in the Sri Lankan Tea (Camellia sinensis L.) and Their Health-Promoting Aspects

Flavonol glycosides in tea leaves have been quantified as aglycones, quercetin, myricetin, and kaempferol. Occurrence of the said compounds was reported in fruits and vegetable for a long time in association with the antioxidant potential. However, data on flavonols in tea were scanty and, hence, this study aims to envisage the flavonol content in a representative pool of accessions present in ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Molecules

دوره 20 12  شماره 

صفحات  -

تاریخ انتشار 2015