Vogt-Koyanagi-Harada syndrome, a rare association of Hodgkin's disease.
نویسندگان
چکیده
Vogt-Koyanagi-Harada syndrome (VKHS) is a well-documented clinical entity. We report the case of a 24 year old man who, within 5 months of the diagnosis of VKHS, developed Hodgkin's disease. Like VKHS, the aetiology of Hodgkin's disease is unknown. A viral factor has been suspected in the pathogenesis of both conditions. Similar immunological abnormalities have been described in both, and may be important predisposing factors.
منابع مشابه
New insights into Vogt-Koyanagi-Harada disease.
Vogt-Koyanagi-Harada disease (VKH), a well-established multiorgan disorder affecting pigmented structures, is an autoimmune disorder of melanocyte proteins in genetically susceptible individuals. Several clinical and experimental data point to the importance of the effector role of CD4+ T cells and Th1 cytokines, the relevance of searching a target protein in the melanocyte, and the relevance o...
متن کاملApplicability of the 2001 revised diagnostic criteria in Brazilian Vogt-Koyanagi-Harada disease patients.
PURPOSE To determine the applicability of the international revised diagnostic criteria for Vogt-Koyanagi-Harada disease. METHODS Retrospective study. Medical charts of 140 patients with the diagnosis of Vogt-Koyanagi-Harada disease, from the Uveitis Sector of the Federal University of Sao Paulo (UNIFESP), were revised and classified following the revised diagnostic criteria. RESULTS Of the...
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Vogt Koyanagi Harada disease (VKH) is a multisystem disorder of an unknown, possibly immune etiology. Sympathetic ophthalmia is also a bilateral panuveitis of presumed immune origin where the inciting stimulus is an injury to the eyeball. The etiopathogenesis of these two diseases which manifest as panuveitis remains poorly understood. In this review, an effort is made to draw a possible etiolo...
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Vogt-Koyanagi-Harada syndrome is an autoimmune multisystem disease, characterized by the association of ocular inflammatory manifestations (uveitis and retinal detachment) and extraocular lesions such as meningismus and tegumentary or auditory findings. We report the case of a Hispanic woman with this syndrome.
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Background: First recognized at the beginning of twentieth century and named after three authors who independently described some affected patients, Vogt-Koyanagi-Harada syndrome is a rare multisystemic autoimmune disease targeting melanin-containing tissues of the eye, meninges, inner ear and skin. It predominantly affects Asian people, but also people with darker skin pigmentation such as Nat...
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ورودعنوان ژورنال:
- Postgraduate medical journal
دوره 67 787 شماره
صفحات -
تاریخ انتشار 1991