Improving reverse neuroimaging inference: cognitive domain versus cognitive complexity.

in brain areas usually associated with both the trigger sensation and the secondary sensation. For example, activation in left colour-sensitive cortex occurred in word– colour synaesthetes hearing words [14] but not in nonsynaesthetes trained to associate colour with words [15]. Many issues concerning the anatomy underlying information processing in synaesthesia remain to be elucidated but this method of using interference techniques to investigate whether synaesthesia involves the same sensory multimodal areas that support cross-modal integration in non-synaesthetes is an important approach. The two immediate questions that pose themselves are how Esterman et al.’s finding will generalize to other synaesthetes and whether the timing of the putative synaesthetic binding is similar to that of sensory integration in non-synaesthetes.