Control of Transcription through Intragenic Patterns of Nucleosome Composition
نویسندگان
چکیده
Several recent papers show that differences in histone modification and the use of histone variants at the 5' and 3' ends of genes influence the location and kinetics of transcriptional initiation. The ultimate target of most epigenetic mechanisms may be the regulation of nucleosome occupancy, which in turn controls access to DNA at specific genomic locations.
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ورودعنوان ژورنال:
- Cell
دوره 123 شماره
صفحات -
تاریخ انتشار 2005