Visible light-mediated dehydrogenative β-arylsulfonylation of tertiary aliphatic amines with arylsulfonyl chlorides.
نویسندگان
چکیده
The novel synthesis of β-arylsulfonyl enamines has been achieved by visible light-mediated dehydrogenative arylsulfonylation of tertiary aliphatic amines with arylsulfonyl chlorides in moderate yield.
منابع مشابه
Visible light-induced 3-sulfenylation of N-methylindoles with arylsulfonyl chlorides.
The synthesis of 1-methyl-3-(arylthio)-1H-indoles has been achieved by the photoredox reaction of N-methylindoles with readily available arylsulfonyl chlorides in moderate yields.
متن کاملSynthesis of benzimidazoles via iridium-catalyzed acceptorless dehydrogenative coupling.
Iridium-catalyzed acceptorless dehydrogenative coupling of tertiary amines and arylamines has been developed. A number of benzimidazoles were prepared in good yields. An iridium-mediated C-H activation mechanism is suggested. This finding represents a novel strategy for the synthesis of benzimidazoles.
متن کاملCopper-catalyzed arylsulfonylation of N-arylsulfonyl-acrylamides with arylsulfonohydrazides: synthesis of sulfonated oxindoles.
A copper-catalyzed arylsulfonylation of N-arylsulfonyl-acrylamides with sulfonylhydrazides through a tandem radical process was developed. This methodology provided an alternative strategy for the synthesis of sulfonated oxindoles by forming C-S, C-N and C-C bonds in a single operation.
متن کاملDIAD-mediated metal-free cross dehydrogenative coupling between tertiary amines and a-fluorinated sulfones†
Fluorinated amines, especially b-fluorinated amines, have received much attention in bioorganic and medicinal chemistry research due to the profound change of the basicity of the amine functionality imparted by fluorine substitution, which has dramatic and beneficial influences on the bioavailability of a target molecule. Among various methods for synthesizing fluorinated amines, nucleophilic f...
متن کاملA visible-light-promoted radical reaction system for azidation and halogenation of tertiary aliphatic C-H bonds.
A highly tunable radical-mediated reaction system for the functionalization of tertiary aliphatic C-H bonds was developed. Reactions of various substrates with the Zhdankin azidoiodane reagent 1, Ru(bpy)3Cl2, and visible light irradiation at room temperature gave C-H azidated or halogenated products in an easily controllable fashion. These reactions are efficient, selective, and compatible with...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Organic & biomolecular chemistry
دوره 12 46 شماره
صفحات -
تاریخ انتشار 2014