Misregulation of pre-mRNA splicing that causes human diseases. Concepts and therapeutic strategies
نویسندگان
چکیده
Abbreviat ions : adrenocorticotrophic hormone, (ACTH); casein kinase I, (CKI); Cdc2-like kinase, (Clk); Concanavalin A, (ConA); cystic fibrosis transmembrane conductance regulator, (CFTR); epidermal growth factor, (EGF); exonic splicing enhancer, (ESE); exonic splicing silencer, (ESS); fibroblast growth factor, (FGF); heterogeneous nuclear protein, (hnRNP); interferon, (IFN); interleukin, (IL); intronic splicing enhancer, (ISE); intronic splicing silencer, (ISS); mitogen-activated protein kinase kinase, (MKK); nerve growth factor, (NGF); Phosphatidylinositide-3-kinase, (PI3-K); platelet-derived growth factor, (PDGF); polymerase II, (polII); protein kinase C, (PKC); protein kinase G-I, (PKG-I); protein tyrosine phosphatase 1B, (PTP-1B); protein with serine-arginine-rich domain, (SR)-protein; signal transduction and activation of RNA, (STAR); small nuclear riboprotein, (snRNP); SR protein kinase, (SRPK); src associated in mitosis, (SAM68); systematic evolution of ligands by exponential enrichment, (SELEX); T cell receptor, (TCR); tumor necrosis factor, (TNF); U2 auxiliary factor, (U2AF); untranslated region, (UTR)
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