Nonsteroidal anti-inflammatory drugs and postoperative bleeding following adenotonsillectomy in pediatric patients.
نویسندگان
چکیده
OBJECTIVE To assess the effects of nonsteroidal anti-inflammatory drugs (NSAIDs) on bleeding for pediatric adenotonsillectomy in a retrospective study, based on the common practices at 2 different tertiary care facilities. DESIGN A retrospective study. SETTING Two different tertiary care facilities. PATIENTS Children up to 16 years of age, who underwent elective adenotonsillectomy or tonsillectomy, were included in the study. All indications for adenotonsillectomy, and all surgical techniques were included. Children with a bleeding tendency, and those with contraindications to the use of NSAIDs (eg, because of allergy), were excluded from the study. INTERVENTIONS Nonsteroidal anti-inflammatory drugs. MAIN OUTCOME MEASURE Postoperative bleeding in patients. RESULTS A total of 1160 patients were selected who met the criteria: 673 patients underwent an adenotonsillectomy or tonsillectomy and did not receive any preoperative and postoperative ibuprofen, and 487 patients underwent routine adenotonsillectomy or tonsillectomy and were given postoperative ibuprofen. We noted a 0.7% postoperative bleeding rate in patients who were not allowed to take ibuprofen perioperatively. There was a 1.0% postoperative bleeding rate in patients who were allowed to take ibuprofen perioperatively (P = .75). CONCLUSION Ibuprofen is not a contraindication to adenotonsillectomy or tonsillectomy and should be used in the control of postoperative pain if it is indicated in the patient.
منابع مشابه
Sequential clot strength analyses following diclofenac in pediatric adenotonsillectomy.
BACKGROUND Tonsillectomy is a common pediatric surgical procedure resulting in significant postoperative pain. There is ongoing controversy as to the most satisfactory analgesic regimen. Nonsteroidal antiinflammatory drugs (NSAIDs) are an alternative to opioids in this setting. NSAID use in tonsillectomy has been shown to be opioid sparing in the recovery period and to have similar analgesic ef...
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Background Non-Steroidal Anti-Inflammatory Drugs(NSAIDs) including Ibuprofen is one of the most currently used drugs in all age groups and finding the relation between upper gastrointestinal bleeding and Helicobacter pylori (H. pylori) in children who used Ibuprofen, is our topic of research. Materials and Methods During the two years of the study, ten children with upper GI bleeding after Ibup...
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OBJECTIVE To use standard meta-analysis techniques to determine the risk of postoperative hemorrhage associated with the use of nonsteroidal anti-inflammatory drugs (NSAIDs) after tonsillectomy. DATA SOURCES The MEDLINE database (1966-2001) restricted to the English language was searched using the keywords tonsillectomy, hemorrhage, analgesics, and NSAID in various combinations. Additionally,...
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متن کاملAnti-inflammatory drugs in the texts of traditional Iranian Medicine (Tim)
Nonsteroidal anti-inflamatory drugs (NSAIDs) and glucocorticoids, nowaday are the main groups of anti-inflamatory drugs in modern pharmacology. The side effects of these antiinflamatory drugs, specially using in chronic diseases cause many problems for the patients and the physicians, so finding the new anti-inflamatory drugs with less side effect is the aim of many researchers. WHO emphasiz to...
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ورودعنوان ژورنال:
- Archives of otolaryngology--head & neck surgery
دوره 134 1 شماره
صفحات -
تاریخ انتشار 2008