Investigate the relation of procalcitonin and prognosis in severe septic patients in SICU
نویسندگان
چکیده
Methods To Collect 64 cases with severe sepsis hospitalized in SICU of the First Affiliated hospital of Sun Yat-sen University from December 2012 to December 2013, retrospectively. Monitored the dynamic changes of serum PCT, C-reactive protein(CRP), vital signs, blood routine test on the 1, 3 and 7 day after admission to SICU, the Acute Physiology and Chronic Health Evaluation II (APACHE II) scores were recorded. Compared the serum PCT, APACHE II, white blood cell(WBC), CRP and other inflammation markers between the two groups. The correlation of PCT and APACHE II was evaluated by spearman correlation analysis. The prediction of mortality of the PCT and APACHE II were evaluated by ROC curves.
منابع مشابه
Predicting treatment failure in severe sepsis and septic shock: looking for the Holy Grail
Procalcitonin has been proposed as a specific biomarker of bacterial infections and has been related to the severity of sepsis. The prognostic ability of the initial concentrations of procalcitonin in sepsis is controversial. Some studies find higher initial concentrations in non-survivors but others find no differences. Prognostic assessment based on follow-up of procalcitonin levels may be be...
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