Inactivation of Retinoblastoma Protein Does Not Overcome

Inactivation of Retinoblastoma Protein Does Not Overcome 1 the Requirement for Human Cytomegalovirus UL97 2 in Lamina Disruption and Nuclear Egress 3 Natalia I. Reim, Jeremy P. Kamil, Depeng Wang, Alison Lin, Mayuri 4 Sharma, Maria Ericsson, Jean M. Pesola, David E. Golan, and Donald M. Coen 5 Running Title: HPV16 E7 does not replace HCMV UL97 for nuclear egress 6 1 Department of Biological Chemistry and Molecular Pharmacology, and 7 2 Electron Microscopy Core Facility, Department of Cell Biology, Harvard Medical 8 School, Boston, MA. 9 3 Department of Microbiology and Immunology, Louisiana State University Health 10 Sciences Center Shreveport, Shreveport, LA. 11 4 Division of Hematology, Brigham and Womens Hospital, Boston, MA 12 † These authors contributed equally to this work. 13 *Corresponding authors, Mailing addresses: 14 Jeremy P. Kamil, 1501 Kings Highway, P.O. Box 33932, Department of Microbiology 15 and Immunology, Louisiana State University Health Sciences Center Shreveport, 16 Shreveport, LA 71130-3932 17 Phone: 318-675-5771, Fax: 318-675-5764, [email protected] 18 Donald M. Coen, Department of Biological Chemistry and Molecular Pharmacology, 19 Harvard Medical School, 20 250 Longwood Ave, Boston, MA 02115 21 Phone: 617-432-1691; Fax: 617-432-3833; Email: [email protected] 22 23 24 Copyright © 2013, American Society for Microbiology. All Rights Reserved. J. Virol. doi:10.1128/JVI.00007-13 JVI Accepts, published online ahead of print on 20 February 2013