Circulating IL-6 level and presence of colorectal adenoma
نویسندگان
چکیده
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Circulating IL-6 level and presence of colorectal adenoma 2 Running title Circulating IL-6 level and presence of colorectal adenoma No financial support was received for this study. Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited.
منابع مشابه
Human Cancer Biology Serum Interleukin-6, Insulin, andHOMA-IR inMale Individuals with Colorectal Adenoma
Purpose: It is widely acknowledged that chronic low-grade inflammation plays a key role in the development of obesity-related insulin resistance and type 2 diabetes. The level of circulating interleukin-6 (IL-6), one of themajor proinflammatory adipokines, is correlatedwith obesity and insulin resistance, which are known to be risk factors for colorectal adenoma. We examined the association bet...
متن کاملNo Association between Circulating Levels and Genetic Variants of IL-6 and TNF-α and Colon Adenoma
BACKGROUND & AIMS Interleukin 6 (IL-6) and tumor necrosis factor alpha (TNF-α), two important inflammatory cytokines, have been inconsistently associated with risk of colon neoplasia in epidemiological studies. However, research to date has not adequately assessed whether race-specific differences may exist in associations between biomarkers and genetic variants of these cytokines and colorecta...
متن کاملIL-6 Plays Crucial Roles in Sporadic Colorectal Cancer through the Cytokine Networks including CXCL7
IL-6 is a multifunctional cytokine and involved in variety of carcinogenesis. However, the association between IL-6 and sporadic colorectal cancer has not been fully explained. Here, we investigated the role of IL-6 signaling and the cytokine network in sporadic colorectal cancer. We investigated the serum IL-6 levels in patients with sporadic colorectal adenoma, cancer patients, and normal con...
متن کاملAssociations of Circulating Inflammatory Biomarkers with Risk Factors for Colorectal Cancer in Colorectal Adenoma Patients
Obesity and central adiposity are associated with colorectal cancer risk and have been linked to inflammation. Inflammation is a complex, interactive response that may most accurately be summarized through multiple, simultaneously measured cytokines. In this cross-sectional analysis, we investigated associations of circulating plasma levels of C-reactive protein (CRP), tumor necrosis factor-α (...
متن کاملMarkers of systemic inflammation and colorectal adenoma risk: Meta-analysis of observational studies
AIM To perform a meta-analysis of observational studies on inflammatory markers levels and occurrence of colorectal adenoma. METHODS PubMed and EMBASE databases were searched until March 2016 for the articles reporting on the circulating levels of inflammatory markers, including: C-reactive protein (CRP), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α) and risk of colorectal ade...
متن کامل