Evaluation of Thin Layer Chromatography Image Analysis Method for Irradiated Chlorpromazine Quantification
نویسندگان
چکیده
We report the use of TLC image analysis software, JustTLC, for identification and quantitative evaluation of the photoproducts generated by the irradiation of Chlorpromazine water solutions with a 266 nm laser beam. The percent concentrations resulting for photoproducts from TLC analysis were compared with the relative concentrations of those identified by LC-TOF/MS measurements. The spots on the analyzed TLC plate were attributed to the corresponding photoproducts. Although LC-MS methods are more accurate, TLC can be successfully used to quantify the photoproducts obtained after exposure to UV laser radiation.
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