Enantioselective Synthesis of the Elaiophylin Aglycon.
نویسندگان
چکیده
Elaiophylin (1) was isolated in 1959 by Arcamone and co-workers from cultures of Streptomyces melanosporus.1 Subsequently, this natural product has also been obtained from other strains of Streptomyces.2 Structure elucidation of 1, including assignment of absolute stereochemistry, was based on chemical degradation,3 NMR studies,4 and ultimately X-ray crystallographic analysis.5 Isolation and characterization of the elaiophylin aglycon, elaiolide (2), was accomplished by Zeeck and Bindseil in 1993 through deglycosylation of 1.6
منابع مشابه
Enantioselective synthesis of the lomaiviticin aglycon full carbon skeleton reveals remarkable remote substituent effects during the dimerization event.
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ورودعنوان ژورنال:
- The Journal of organic chemistry
دوره 62 3 شماره
صفحات -
تاریخ انتشار 1997