A Study of Gastro – Intestinal Helminths in Native Peafowl and Comparative Efficacy of Albendazole and Pyrantel Pamoate against the Helminth Parasites
نویسندگان
چکیده
Received: Revised: Accepted: 2013–11–17 2014–02–28 2014–03–04 The study was conducted to determine the infection rate of helminths in peafowls and to evaluate the comparative efficacy of two broad spectrum anthelmintics. For this purpose, fecal samples of 87 different breeds of peafowls were collected and tested for the presence of helminths. Fecal samples were examined by direct smear and centrifugal floatation methods for qualitative examination. For quantitative examination McMaster Egg Counting Technique was used. We found that 56.32% (49 out of 87) peafowls were positive for gastrointestinal helminths. Single or mixed infection of Heterakis gallinae, Ascaridia galli, Davainea proglottina, Capillaria columbae and Acuaria spiralis was present with their individual percentage was 36.73%, 26.53%, 6.12%, 18.37% and 12.24%, respectively. Out of these 49 birds 48 positive birds were divided in 3 groups A, B and C, each comprising of 16 birds. The uninfected and untreated birds were kept in group D. Chemotherapeutic trials were conducted to the birds of group A and B. While group C served as positive control and group D served as negative control for chemotherapeutic trials. Group A was treated with Albendazole 0.1ml/kg body weight and group B was treated with Pyrantel pamoate (0.1 mL /kg body weight). We found that Albendazole is more effective against gastrointestinal helminths having 94.92% efficacy as compare to Pyrantel pamoate which showed 78.34% efficacy on 10 day of drug treatment. All copyrights reserved to Nexus® academic publishers
منابع مشابه
Failure of pyrantel in treatment of human hookworm infections (Ancylostoma duodenale) in the Kimberley region of north west Australia.
A survey of 108 individuals from a coastal Aboriginal community in north Western Australia revealed that two species of gastrointestinal protozoan parasites (Giardia duodenalis--39.8%, Entamoeba coli--40.7%) and five gastrointestinal helminths (Hymenolepis nana--54.6%, Hookworm [Ancylostoma duodenale]--30.6%, Enterobius vermicularis--6.5%, Trichuris trichiura--2.8%, Strongyloides stercoralis 1....
متن کاملTreatment of mixed Oesophagostomum and hookworm infection: effect of albendazole, pyrantel pamoate, levamisole and thiabendazole.
Oesophagostomum bifurcum has recently been recognized as a common parasite of man in northern Togo and in Ghana. In a preliminary trial several anthelmintics were evaluated in the treatment of mixed Oesophagostomum and hookworm infections. Diagnosis was based on faecal culture, since the eggs of Oesophagostomum and hookworm cannot be distinguished morphologically. Of the anthelmintics tested, a...
متن کاملAscaris lumbricoides: an overview of therapeutic targets.
A. lumbricoides is the largest of the common nematode parasites of man and has been associated with intestinal pathology, respiratory symptoms and malnutrition in children from endemic areas. Current anthelmintic treatments have proven to be safe. However, a reduced efficacy of single dose drugs has been reported. In veterinary practice, anthelmintic drug resistance is an irreversible problem. ...
متن کاملEfficacy of recommended drugs against soil transmitted helminths: systematic review and network meta-analysis
Objective To evaluate efficacies of anthelmintic drugs against soil transmitted helminths in terms of cure rates and egg reduction rates.Design Systematic review and network meta-analysis.Data Sources PubMed, ISI Web of Science, Embase, ScienceDirect, the Cochrane Central Register of Clinical Trials, and the World Health Organization library database from 1960 until 31 December 2016.Study selec...
متن کاملComparative efficacy of Levamisole, Mebendalzole and Pyrantel Pamoate against common intestinal nematodes among children in Calabar, South-South Nigeria
Introduction: Continued endemicity of intestinal nematodes infestation in children in our environment despite availability of potent and safe anthelmintic drugs is of public health interest. Objective: This study assessed the comparative efficacy of selected anthelmintic drugs namely Mebendazole, pyrantel pamoate and levamisole-against common intestinal nematodes namely Ascaris lumbricoides, Ho...
متن کامل