What the Dead Can Teach the Living: The Systemic Nature of Heart Failure with Preserved Ejection Fraction Running title: Kitzman et al.; Systemic Nature of HFPEF

نویسندگان

  • Dalane W. Kitzman
  • Bharathi Upadhya
  • Sujethra Vasu
چکیده

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What the dead can teach the living: systemic nature of heart failure with preserved ejection fraction.

H eart failure (HF) with preserved ejection fraction (HFpEF) is the most common form of HF. Approximately 90% of new HF cases in older women are HFpEF. 1 Adverse outcomes – exercise intolerance, poor quality of life, frequent hospitalizations , and reduced survival – approach those of HF with reduced EF (HFrEF). In contrast to HFrEF, the prevalence of HFpEF is increasing and its prognosis is wo...

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Exercise Hemodynamics Enhance Diagnosis of Early Heart Failure with Preserved Ejection Fraction Running Title: Exercise Hemodynamics in Early HFpEF

Subject Codes: 110 (congestive heart failure), 26 (exercise) df df df df df df dfie ie ie ie ie ie ield ld ld ld ld ld ABSTRACT Background: When advanced, heart failure (HF) with preserved ejection fraction (HFpEF) is

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Phenotype-Specific Treatment of Heart Failure With Preserved Ejection Fraction: A Multiorgan Roadmap.

Heart failure (HF) with preserved ejection fraction (EF; HFpEF) accounts for 50% of HF cases, and its prevalence relative to HF with reduced EF continues to rise. In contrast to HF with reduced EF, large trials testing neurohumoral inhibition in HFpEF failed to reach a positive outcome. This failure was recently attributed to distinct systemic and myocardial signaling in HFpEF and to diversity ...

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Transcatheter Interatrial Shunt Device for the Treatment of Heart Failure

Prevalence of Heart Failure With Preserved Left Ventricular Ejection Fraction More than one-half of people with heart failure (HF) have a preserved left ventricular ejection fraction (HFpEF). Patients with HFpEF, commonly referred to as diastolic HF, have symptoms and/or signs of HF and a left ventricular ejection fraction (LVEF) >40% to 50%. The prevalence of HFpEF exceeds 3 million in the Uni...

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تاریخ انتشار 2014