CLINICAL TRIALS AND OBSERVATIONS The role of maintenance thalidomide therapy in multiple myeloma: MRC Myeloma IX results and meta-analysis
نویسندگان
چکیده
1Institute of Cancer Research, Royal Marsden Hospital, London, United Kingdom; 2Clinical Trials Research Unit, University of Leeds, Leeds, United Kingdom; 3St James’s University Hospital, Leeds, United Kingdom; 4Nottingham University Hospital, Nottingham, United Kingdom; 5Royal Devon and Exeter Hospital, Exeter, United Kingdom; 6Western General Hospital, Edinburgh, United Kingdom; 7University of Birmingham, Birmingham, United Kingdom; 8Wessex Regional Genetics Laboratory, University of Southampton, Salisbury, United Kingdom; and 9University of Newcastle, Newcastle-upon-Tyne, United Kingdom
منابع مشابه
CLINICAL TRIALS AND OBSERVATIONS Thalidomide for previously untreated elderly patients with multiple myeloma: meta-analysis of 1685 individual patient data from 6 randomized clinical trials
Peter M. Fayers,1,2 Antonio Palumbo,3 Cyrille Hulin,4 Anders Waage,2,5 Pierre Wijermans,6 Meral Beksaç,7 Sara Bringhen,8 Jean-Yves Mary,9 Peter Gimsing,10 Fabian Termorshuizen,11 Rauf Haznedar,12 Tommaso Caravita,13 Philippe Moreau,14 Ingemar Turesson,15 Pellegrino Musto,16 Lotfi Benboubker,17 Martijn Schaafsma,18 Pieter Sonneveld,19 and Thierry Facon,20 on behalf of the Nordic Myeloma Study Gr...
متن کاملCLINICAL TRIALS AND OBSERVATIONS Maintenance therapy with thalidomide improves survival in patients with multiple myeloma
Michel Attal, Jean-Luc Harousseau, Serge Leyvraz, Chantal Doyen, Cyrille Hulin, Lofti Benboubker, Ibrahim Yakoub Agha, Jean-Henri Bourhis, Laurent Garderet, Brigitte Pegourie, Charles Dumontet, Marc Renaud, Laurent Voillat, Christian Berthou, Gerald Marit, Mathieu Monconduit, Denis Caillot, Bernard Grobois, Herve Avet-Loiseau, Philippe Moreau, and Thierry Facon, for the Inter-Groupe Francophone...
متن کاملCLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS Superiority of thalidomide and dexamethasone over vincristine-doxorubicin- dexamethasone (VAD) as primary therapy in preparation for autologous transplantation for multiple myeloma
The aim of the present study was to compare thalidomide-dexamethasone (Thal-Dex) and vincristine-doxorubicindexamethasone (VAD) as primary therapy in preparation for autologous peripheral blood stem-cell (PBSC) transplantation for multiple myeloma (MM). For this purpose, we performed a retrospective matched case-control analysis of 200 patients who entered 2 consecutive studies from 1996 to 200...
متن کاملCLINICAL TRIALS AND OBSERVATIONS Lenalidomide plus dexamethasone is more effective than dexamethasone alone in patients with relapsed or refractory multiple myeloma regardless of prior thalidomide exposure
1Department of Lymphoma and Myeloma, M. D. Anderson Cancer Center, Houston, TX; 2Department of Clinical Therapeutics, University of Athens School of Medicine, Athens, Greece; 3Department of Medicine, Princess Margaret Hospital, Toronto, ON; 4Hematology Department, Institute of Hematology and Oncology, Hospital Clinic, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universit...
متن کاملRegular Article CLINICAL TRIALS AND OBSERVATIONS A randomized phase 3 trial of thalidomide and prednisone as maintenance therapy afterASCT in patients with MM with a quality-of-life assessment: the National Cancer Institute of Canada Clinicals Trials Group Myeloma 10 Trial
A. Keith Stewart,1 Suzanne Trudel,2 Nizar J. Bahlis,3 Darrell White,4 Waleed Sabry,5 Andrew Belch,6 Tony Reiman,7 Jean Roy,8 Chaim Shustik,9 Michael J. Kovacs,10 Morel Rubinger,11 Guy Cantin,12 Kevin Song,13 Kirsty A. Tompkins,14 Deb C. Marcellus,15 Martha Q. Lacy,16 Jonathan Sussman,15 Donna Reece,2 Michael Brundage,17 Erica L. Harnett,18 Lois Shepherd,18 Judy-Anne W. Chapman,18 and Ralph M. M...
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