CALL FOR PAPERS Integrative and Translational Physiology: Inflammation and Immunity in Organ System Physiology Subclinical exposure to low-dose endotoxin impairs EEG maturation in preterm fetal sheep
نویسندگان
چکیده
Michael J. Keogh, Laura Bennet, Paul P. Drury, Lindsea C. Booth, Sam Mathai, Andrew S. Naylor, Mhoyra Fraser, and Alistair J. Gunn Department of Physiology, University of Auckland, Auckland, New Zealand; Institute of Genetic Medicine, International Centre for Life, Newcastle University, Newcastle Upon Tyne, United Kingdom; Howard Florey Institute, University of Melbourne, Melbourne, Australia; and Liggins Institute, University of Auckland, Auckland, New Zealand
منابع مشابه
Subclinical exposure to low-dose endotoxin impairs EEG maturation in preterm fetal sheep.
Exposure to chorioamnionitis is strongly associated with neurodevelopmental disability after premature birth; however, it remains unclear whether subclinical infection affects functional EEG maturation. Chronically instrumented 103-104-day-old (0.7 gestational age: term 147 days) fetal sheep in utero were randomized to receive either gram-negative LPS by continuous low-dose infusion (100 ng iv ...
متن کاملCALL FOR PAPERS Integrative and Translational Physiology: Inflammation and Immunity in Organ System Physiology Acute on chronic exposure to endotoxin in preterm fetal sheep
Mathai S, Booth LC, Davidson JO, Drury PP, Fraser M, Jensen EC, George S, Naylor A, Gunn AJ, Bennet L. Acute on chronic exposure to endotoxin in preterm fetal sheep. Am J Physiol Regul Integr Comp Physiol 304: R189–R197, 2013. First published December 12, 2012; doi:10.1152/ajpregu.00388.2012.—Acute, high-dose exposure to endotoxin lipopolysaccharide (LPS) in preterm fetal sheep can trigger peri...
متن کاملCALL FOR PAPERS Integrative and Translational Physiology: Inflammation, Immunity, and Organ System Physiology Biphasic changes in fetal heart rate variability in preterm fetal sheep developing hypotension after acute on chronic lipopolysaccharide exposure
Lear CA, Davidson JO, Booth LC, Wassink G, Galinsky R, Drury PP, Fraser M, Bennet L, Gunn AJ. Biphasic changes in fetal heart rate variability in preterm fetal sheep developing hypotension after acute on chronic lipopolysaccharide exposure. Am J Physiol Regul Integr Comp Physiol 307: R387–R395, 2014. First published June 18, 2014; doi:10.1152/ajpregu.00110.2014.—Perinatal exposure to infection ...
متن کاملAcute on chronic exposure to endotoxin in preterm fetal sheep.
Acute, high-dose exposure to endotoxin lipopolysaccharide (LPS) in preterm fetal sheep can trigger periventricular white matter lesions (PVL), in association with severe hypotension/hypoxemia and significant mortality. Intriguingly, however, chronic or repeated exposure to LPS can induce tachyphylaxis. We therefore tested the hypothesis that progressive, acute on chronic fetal infection would b...
متن کاملCALL FOR PAPERS Integrative and Translational Physiology: Inflammation and Immunity in Organ System Physiology Acute on chronic exposure to endotoxin is associated with enhanced chemoreflex responses in preterm fetal sheep
Booth LC, Drury PP, Muir C, Jensen EC, Gunn AJ, Bennet L. Acute on chronic exposure to endotoxin is associated with enhanced chemoreflex responses in preterm fetal sheep. Am J Physiol Regul Integr Comp Physiol 304: R799–R803, 2013. First published March 13, 2013; doi:10.1152/ajpregu.00005.2013.—There is increasing evidence that exposure to infection can sensitize the fetus to subsequent hypoxic...
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تاریخ انتشار 2012