Week-day variation in clinical chemical analyses.

the fast-moving variants, and the homozygotes as shown in Figure 1. (Recently I have also detected a case of heterozygosity of transferrin and complement component C3). However, it is always necessary to keep in mind that a1-antitrypsin heterozygosity is not the only cause of a1 zone-splitting. In fact, in one case the additional band was a-fetoprotein (1). In my experience the better way to ascertain the cause of the splitting is the immunosubtraction electrophoresis technique (2), which in this case consists of the immunoprecipitation of a1-antitrypsin at the beginning of the electrophoretic run. In the caseof a1-antitrypsin heterozygosity the two ai bands will disappear. By the immunofixation technique the results are not so good because the close proximity of the two bands almost always causes the immunoprecipitates to fuse.