Protective role of Mannose binding Lectin (MBL2) promoter haplotypes on TB infection in South Indian HIV-1 patients
نویسندگان
چکیده
Conclusion In this study, we could observe MBL2 promoter haplotypes with low MBL secretion may play a protective role to intracellular mycobacterium infections like TB in HIV seropositive individuals. Authors’ details Department of Immunology, School of Biological Sciences, Madurai Kamaraj University, Madurai625021, India. ART Centre, Govt. Theni Medical College and Hospital, Theni625512, India.
منابع مشابه
The role of mannose-binding lectin gene polymorphisms in susceptibility to HIV-1 infection in Southern Brazilian patients.
OBJECTIVE This study investigates the role of mannose-binding lectin (MBL) in the susceptibility to HIV-1 infection analyzing polymorphisms located at the MBL2 promoter and exon 1 regions. MATERIALS AND METHODS The prevalence of MBL2 variant alleles was investigated in 410 HIV-1-infected patients from the South Brazilian HIV cohort and in 345 unexposed uninfected healthy individuals. The prom...
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