Recent advances in the treatment of age-related macular degeneration.

Transpupilary thermotherapy of occult subfoveal choroidal neovascularization secondary to age related macular degeneration

 Abstract Background: Transpupillary thermotherapy is a new treatment for subfoveal choroidal neovascularization which needs further evaluation. This study was aimed to evaluate the efficacy of transpupillary thermotherapy on regression of occult subfoveal choroidal neovascularization with or without pigment epithelial detachment in patients with age-related macular degeneration. Methods: In a ...

Decision Support System for Age-Related Macular Degeneration Using Convolutional Neural Networks

Introduction: Age-related macular degeneration (AMD) is one of the major causes of visual loss among the elderly. It causes degeneration of cells in the macula. Early diagnosis can be helpful in preventing blindness. Drusen are the initial symptoms of AMD. Since drusen have a wide variety, locating them in screening images is difficult and time-consuming. An automated digital fundus photography...

همراهی پلی‌مورفیسم p.Gly119Arg ژن CFI در مبتلایان به بیماری دژنراسیون ماکولای وابسته به سن در جمعیت ساکن در شهر تهران

Background: Age-related macular degeneration (AMD) is the leading cause of blindness in the developed world and is characterized by progressive degeneration of the retinal pigment epithelium and secondary photoreceptor loss, resulting in visual loss. Etiological research suggests that age related macular degeneration is a complex disease, caused by the interactions of several genetic and enviro...

Recent advances in the management and understanding of macular degeneration

Current management of age-related macular degeneration (AMD) is directed at intravitreal injection of vascular endothelial growth factor (VEGF) inhibitors for the treatment of wet AMD and supplementation with oral antioxidants for the treatment of dry AMD. In this article, we will review recent clinical trials for the treatment of dry and wet AMD.

Recent advances and future directions for the pharmacogenetic basis of anti-VEGF treatment response in neovascular age-related macular degeneration

Association of CFI gene polymorphism with age related macular degeneration in Northwest of Iran

Background & Aims: To investigate the association of CFI p.Gly119Arg polymorphism with Age-related macular degeneration (AMD). Materials & Methods: In this case-control study, the association of p.Gly119Arg polymorphism in CFI gene was investigated in 65 patients suffering from AMD and150 healthy age, sex and ethnicity matched unrelated people as control group. Both of the case and cont...