Z-membranes: artificial organelles for overexpressing recombinant integral membrane proteins.
نویسندگان
چکیده
منابع مشابه
Mechanisms for the incorporation of proteins in membranes and organelles
Because of the high degree of organizational complexity of eucaryotic cells, it is clear that the implementation of their genetic programs must, in many cases, involve a complex sequence of cotranslational and posttranslational events that are necessary to transfer polypeptides from their sites of synthesis to their sites of function. It is difficult to envisage the existence of a single genera...
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Peter Rehling is professor and chair of biochemistry at the Faculty of Medicine at the University of Göttingen and the director of the Department for Biochemistry II. His laboratory studies the biogenesis of mitochondria, in particular the molecular mechanism by which proteins are translocated across the mitochondrial membranes and how they assemble into membrane protein complexes. In all cellu...
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The ease with which a cell membrane can bend and deform is important for a wide range of biological functions. Peripheral proteins that induce curvature in membranes (e.g. BAR domains) have been studied for a number of years. Little is known, however, about the effect of integral membrane proteins on the stiffness of a membrane (characterised by the bending rigidity, Kc). We demonstrate by comp...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1996
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.93.5.2219