Whole Brain Radiation Therapy Associated Diffuse Progressive Leukoencephalopathy and Brain Atrophy
نویسندگان
چکیده
منابع مشابه
Incidence of leukoencephalopathy after whole-brain radiation therapy for brain metastases.
PURPOSE To evaluate the incidence of leukoencephalopathy after whole-brain radiation therapy (WBRT) in patients with brain metastases. METHODS AND MATERIALS We retrospectively reviewed 111 patients who underwent WBRT for brain metastases from April 2001 through March 2008 and had evaluable computed tomography (CT) and/or magnetic resonance imaging (MRI) at least 1 month after completion of WB...
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Stereotactic radiosurgery is frequently used, either alone or together with whole-brain radiation therapy to treat brain metastases from solid tumors. Certain experts and radiation oncology groups have proposed replacing whole-brain radiation therapy with stereotactic radiosurgery alone for the management of brain metastases. Although randomized trials have favored adding whole-brain radiation ...
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Advances in the treatment of melanoma with novel systemic therapies have meaningfully increased survival of patients. The brain is a common early site for melanoma metastases. Whole-brain radiation therapy (WBRT) is of limited effectiveness for radioresistant histologies such as melanoma and has been associated with white matter change and cognitive dysfunction. Prior studies of leukoencephalop...
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In multiple system atrophy (MSA) and progressive supranuclear palsy (PSP), the absence of surrogate endpoints makes clinical trials long and expensive. We aim to determine annualized whole-brain atrophy rates (a-WBAR) in idiopathic Parkinson's disease (IPD), MSA, and PSP. Ten healthy controls, 20 IPD, 12 PSP, and 8 MSA patients were studied using a volumetric MRI technique (SIENA). In controls,...
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BACKGROUND Radiation maculopathy is a phenomenon that occurs after radiation exposure. The rapid onset of unilateral macular atrophy without peripheral retinopathy after radiation has rarely been described. METHODS A case report and literature review. RESULTS We report a case of stage 4 non-small cell lung cancer under targeted therapy using Gefitinib who presented with severely impaired vi...
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ژورنال
عنوان ژورنال: Journal of the Korean Neurological Association
سال: 2017
ISSN: 1225-7044,2288-985X
DOI: 10.17340/jkna.2017.3.19