White-light quantitative phase imaging unit

Rapid quantitative phase imaging for partially coherent light microscopy.

Partially coherent light provides promising advantages for imaging applications. In contrast to its completely coherent counterpart, it prevents image degradation due to speckle noise and decreases cross-talk among the imaged objects. These facts make attractive the partially coherent illumination for accurate quantitative imaging in microscopy. In this work, we present a non-interferometric te...

White Light Diffraction Phase Microscopy

Quantitative phase imaging (QPI) techniques are very advantageous compared to the qualitative phase imaging techniques like bright field microscopy, phase contrast microscopy, differential interference contrast microscopy due to measurement of phase information quantitatively. In QPI techniques, there is no need of exogenous contrast agents to stain or tag the specimen. White light diffraction ...

Quantitative Phase Imaging

Pathological Assessment of Brain White Matter in Relapsing-Remitting MS Patients using Quantitative Magnetization Transfer Imaging

Introduction: Multiple sclerosis (MS) is characterized by lesions in the white matter (WM) of the central nervous system. Magnetic resonance imaging is the most specific and sensitive method for diagnosis of multiple sclerosis. However, the ability of conventional MRI to show histopathologic heterogeneity of MS lesions is insufficient. Quantitative magnetization transfer imaging (qMTI) is a rel...

Quantitative Phase Shift Variance Imaging

Molecular ultrasound imaging is based on the detection of contrast agents (microbubbles) targeted to disease specific receptors in the vasculature. By quantifying the amount of the adherent microbubbles a change in the expression of these receptors and thus the disease development can be assessed. Quantification of microbubbles from ultrasound images in vivo was thus far mainly performed by ana...