Use of plasmapheresis in acquired demyelinating syndromes

Background: Patients with acute inflammatory demyelination of the central nervous system (CNS) may present severe neurological impairment, including flaccid quadriparesis and amaurosis. Plasmapheresis (PLEX) is an alternative treatment for patients who do not immediately improve clinically or whom symptoms worsen despite corticosteroid dosing preferred in context serious events.