Use of Intravenous Lipid Emulsions With Parenteral Nutrition: Practical Handling Aspects

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New parenteral lipid emulsions for clinical use.

Routine use of parenteral lipid emulsions (LE) in clinical practice began in 1961, with the development of soybean oil (SO) - based LE. Although clinically safe, experimental reports indicated that SO-based LE could exert a negative influence on immunological functions. Those findings were related to its absolute and relative excess of omega-6 polyunsaturated fatty acids (PUFA) and the low amou...

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Lipid emulsions – Guidelines on Parenteral Nutrition, Chapter 6

The infusion of lipid emulsions allows a high energy supply, facilitates the prevention of high glucose infusion rates and is indispensable for the supply with essential fatty acids. The administration of lipid emulsions is recommended within < or =7 days after starting PN (parenteral nutrition) to avoid deficiency of essential fatty acids. Low-fat PN with a high glucose intake increases the ri...

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Parenteral nutrition-associated liver disease and lipid emulsions.

Parenteral nutrition-associated liver disease (PNALD) is a particularly important problem in patients who need this type of nutritional support for a long time. Prevalence of the condition is highly variable depending on the series, and its clinical presentation is different in adults and children. The etiology of PNALD is not well defined, and participation of several factors at the same time ...

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The use of alternative lipid emulsions in paediatric and neonatal parenteral nutrition

Lipid emulsions are an important part of paediatric parenteral nutrition as they provide energy, fat soluble vitamins and are a source of essential fatty acids. Soya bean based oil emulsions have however been identified as one of the major causative factors in the development of PN related cholestasis. The newer lipid emulsion containing fish oil has been shown to reduce the risk of such compli...

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Effects of postoperative parenteral nutrition with different lipid emulsions in patients undergoing major abdominal surgery

PURPOSE This study was designed to investigate the effects of total parenteral nutrition (PN) using different lipid emulsions in patients undergoing major abdominal surgery. METHODS Fifty-two patients were randomized to receive soybean oil + medium chain triglycerides (MCT) (group I), soybean oil + olive oil (group II), soybean oil + olive oil + fish oil (group III) as a lipid source. PN was ...

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ژورنال

عنوان ژورنال: Journal of Parenteral and Enteral Nutrition

سال: 2020

ISSN: 0148-6071,1941-2444

DOI: 10.1002/jpen.1737