Transport of Prostaglandin E1 across Rat Erythrocyte Membrane
نویسندگان
چکیده
منابع مشابه
Active Transport of Organic Anions across the Human Erythrocyte Membrane
Erythrocytes, which constitute more than 40% of the blood volume and about 3% of the body mass, are an important, although frequently neglected, detoxification organ. The main route of xenobiotic metabolism in erythrocytes goes through the glutathione conjugation process, and subsequently comprises removal of the conjugates via the membrane active transport systems. In human erythrocyte membran...
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Prostaglandin E1 (PGE1) suppresses mitotic activity in the epithelial cells of rat lenses maintained in organ culture. At a concentration of 5 x 10(-5)M, PGE1 caused gradual inhibition of mitosis which was first evident after six hours of incubation and was maximum at 50 per cent of control values after 16 and 24 hours in culture. During this period prostaglandin-treated lenses showed no change...
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Phosphoenolpyruvate was transported through the erythrocyte membrane at low pH (4.5-6.5). The influx was observed not only in an iso-osmotic sucrose medium, but also in 0.1 M-citrate solution, but it was negligible in an iso-osmotic NaC1 solution. Efflux, however, was observed in both the sucrose and NaC1 solutions. Compounds derived from phosphoenolpyruvate by replacing the methene group by si...
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ژورنال
عنوان ژورنال: Biological and Pharmaceutical Bulletin
سال: 2008
ISSN: 0918-6158,1347-5215
DOI: 10.1248/bpb.31.1288