Toluidine blue for extramammary Paget’s disease in Mohs micrographic surgery
نویسندگان
چکیده
Introduction: We report an elderly gentleman with Extramammary Paget’s disease (EMPD) treated Mohs micrographic surgery (MMS) using Toluidine blue staining intraoperatively as to detect the cells. Case Presentation: An man presented erythematous plaque on left inguinal fold which showed in-situ EMPD histopathological examination. Investigations for secondary were negative and patient was MMS. During MMS, specimens from stained in order Paget cells determine appropriate margin. At 4 years follow up is free of recurrence. Conclusion: a fast, user-friendly dye that can be used during MMS thus
منابع مشابه
Extramammary Paget's disease: surgical treatment with Mohs micrographic surgery.
BACKGROUND Extramammary Paget's disease (EMPD) is an uncommon tumor that has a high rate of recurrence after conventional surgical treatments. OBJECTIVE Our purpose was to establish the efficacy of Mohs micrographic surgery (MMS) in the treatment of EMPD, and to make treatment recommendations with regard to surgical margins. We also attempted to summarize the published recurrence rates of EMP...
متن کاملMohs micrographic surgery for extramammary Paget disease: a pooled analysis of individual patient data.
BACKGROUND Extramammary Paget disease (EMPD) is a rare intraepithelial neoplasm of the skin characterized by ill-defined margins and high recurrence rates after wide local excision. Although Mohs micrographic surgery (MMS) has been proposed to decrease the rate of local recurrence, the efficacy of MMS for this condition has not yet been established. OBJECTIVE We sought to assess the efficacy ...
متن کاملDERMATOLOGIC SURGERY Extramammary Paget’s disease: Surgical treatment with Mohs micrographic surgery
Results: The recurrence rate after treatment with MMS was 16% for primary EMPD and 50% for recurrent EMPD. The 5-year tumor-free rates (Kaplan-Meier analysis) were 80% for primary tumors and 56% for recurrent tumors. Using MMS, the salvage rate (and, hence, overall cure rate) was 100%. Margins of 5 cm were required to clear 97% of the tumors. The recurrence rate after non-MMS ( from the literat...
متن کاملMohs micrographic surgery.
Mohs micrographic surgery (MMS) is a specialized type of minimal marginal surgery that offers cure rates superior to other options in the treatment of contiguous skin cancers in selected settings. Developed by Dr. Frederic E. Mohs, the technique originally required in situ tissue fixation before excision. Most Mohs micrographic surgeons now use the fresh tissue technique exclusively. Horizontal...
متن کامل[Extramammary paget disease: report of 2 cases treated by mohs micrographic surgery].
Actas Dermosifiliogr. 2009;100:235-48 239 To the Editor: Extramammary Paget disease (EPD), first described by Crocker1 in 1889, is a rare intraepithelial neoplasia of regions of the skin rich in apocrine glands. The lesions present clinically as erythematous scaly or slightly pruriginous plaques, and histological studies show cells with large cytoplasm and prominent nucleoli throughout the epid...
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ژورنال
عنوان ژورنال: Skin
سال: 2021
ISSN: ['2574-1624']
DOI: https://doi.org/10.25251/skin.5.1.16