To plug or not to plug?

To plug or not to plug?

Coronary artery disease remains a common problem in industrialized countries. Percutaneous coronary interventions are usually performed utilizing the femoral approach. Arterial puncture-closing devices have been developed in hope to avoid manual compression and shortening the period of rest. In a recent meta-analysis in the Journal of the American Medical Association these devices have shown on...

To plug or not to plug: a cost-effectiveness analysis for complex anal fistula.

BACKGROUND Complex anal fistulas are unsuitable for fistulotomy because of the risk of fecal incontinence. The anal fistula plug (AFP) has demonstrated fistula healing without sphincter division. This study aims to evaluate the cost-effectiveness of the AFP compared to the endoanal advancement flap (EAAF) as an alternative sphincter-preserving option for complex anal fistulas. METHODS The stu...

Tempus fugit: How to plug it

Secret or private information may be leaked to an external attacker through the timing behaviour of the system running the untrusted code. After introducing a formalisation of this situation in terms of a confinement property, we present an algorithm which is able to transform the system into one that is computationally equivalent to the given system but free of timing leaks.

Plug-in Approach to Active Learning

We present a new active learning algorithm based on nonparametric estimators of the regression function. Our investigation provides probabilistic bounds for the rates of convergence of the generalization error achievable by proposed method over a broad class of underlying distributions. We also prove minimax lower bounds which show that the obtained rates are almost tight.

Folic Acid Supplementation: to Advise or not to Advise?