TLR5 Activation Exacerbates Airway Inflammation in Asthma
نویسندگان
چکیده
منابع مشابه
IL-33 exacerbates eosinophil-mediated airway inflammation.
IL-33 has emerged as an important mediator in the immunopathogenesis of allergy and asthma. However, the role of IL-33 in eosinophil-mediated inflammation has not been fully explored. In this article, we report that IL-33 directly stimulates eosinophil differentiation from CD117(+) progenitors in an IL-5-dependent manner. Although resting eosinophils expressed moderate levels of the IL-33R alph...
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As bronchial asthma is currently considered to be and is defined as being an inflammatory disorder of the airways [1], it seems logical to include an assessment of this inflammation in the diagnosis and follow-up of the disease. In this assessment, a few factors need to be taken into account. Firstly, the inflammation underlying asthma is a complex phenomenon that displays characteristics, not ...
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ژورنال
عنوان ژورنال: Lung
سال: 2020
ISSN: 0341-2040,1432-1750
DOI: 10.1007/s00408-020-00337-2