Time-Resolved Measurement of State-Specific P2X2 Ion Channel Cytosolic Gating Motions
نویسندگان
چکیده
منابع مشابه
Time-resolved measurement of state-specific P2X2 ion channel cytosolic gating motions.
ATP-gated P2X2 channels undergo permeability changes through a process that is incompletely understood. In the present study, we used fluorescence resonance energy transfer (FRET) and electrophysiology to measure cytosolic gating motions in P2X2 channels as they enter a state with increased permeability. P2X2 channels underwent permeability changes with a time course that was similar to decreas...
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ژورنال
عنوان ژورنال: Journal of Neuroscience
سال: 2004
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.3250-04.2004