The joint–gut axis in inflammatory bowel diseases
نویسندگان
چکیده
منابع مشابه
The joint-gut axis in inflammatory bowel diseases.
Inflammatory bowel diseases, Crohn's disease and ulcerative colitis, are associated with a variety of extraintestinal manifestations. The most common extraintestinal manifestation, articular involvement, occurs in 16% to 33% of inflammatory bowel disease patients. These arthropathies may increase morbidity, resulting in a worse quality of life compared with inflammatory bowel disease patients w...
متن کاملThe Bowel Microbiota and Inflammatory Bowel Diseases
The human bowel contains a large and biodiverse bacterial community known as the microbiota or microbiome. It seems likely that the microbiota, fractions of the microbiota, or specific species comprising the microbiota provide the antigenic fuel that drives the chronic immune inflammation of the bowel mucosa that is characteristic of Crohn's disease and ulcerative colitis. At least twenty years...
متن کامل[Inflammatory bowel diseases]
OBJECTIVE: To present a review about inflammatory bowel diseases in childhood so that pediatricians become familiar with two diseases (ulcerative colitis and Crohn s disease) that are increasing in incidence. METHODS: Articles of specific gastroenterological journals were analyzed. Information was also obtained from the author s extensive professional experience in the area. RESULTS: The two di...
متن کاملInflammatory bowel diseases.
All rights reserved. Unless special permission in writing is obtained, no part of this publication may be reproduced, stored in a retrieval system, or be transmitted in any form or by any means, electronic, mechanical, photocopying or otherwise. The material contained in this issue was submitted as previously unpublished material, except in the instances in which credit has been given to the so...
متن کاملChemokines in inflammatory bowel diseases.
Uncontrolled activation of mucosal effector cells has been identified as the main pathogenic mechanism involved in the initiation and perpetuation of mucosal inflammation in inflammatory bowel diseases (IBD). The sustained activation of these cells leads to the aberrant production of various pro-inflammatory mediators, which co-ordinated action amplifies the inflammatory process. In this settin...
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ژورنال
عنوان ژورنال: Journal of Crohn's and Colitis
سال: 2010
ISSN: 1873-9946
DOI: 10.1016/j.crohns.2009.11.005