The effects of moxonidine, a novel imidazoline, on plasma norepinephrine in patients with congestive heart failure
نویسندگان
چکیده
منابع مشابه
The effects of moxonidine, a novel imidazoline, on plasma norepinephrine in patients with congestive heart failure. Moxonidine Investigators.
OBJECTIVE To evaluate the dose response relationship of moxonidine on plasma concentration of norepinephrine during acute and chronic administration in patients with congestive heart failure (CHF). BACKGROUND Sympathetic activation is increased in heart failure. Moxonidine is an imidazoline ligand acting on the central nervous system (CNS) receptors to decrease sympathetic activation. METHO...
متن کاملEffects of sustained-release moxonidine, an imidazoline agonist, on plasma norepinephrine in patients with chronic heart failure.
BACKGROUND In chronic heart failure, sympathetic activation is increased. Moxonidine acts on central nervous system receptors to decrease sympathetic activation. We investigated the dose-response relationship of a new sustained-release (SR) preparation of moxonidine and the plasma concentration of norepinephrine in patients with chronic heart failure. METHODS AND RESULTS A total of 268 patien...
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During a period of four years between June, IS, 1988 to June, IS, 1992 one hundred and fourteen patients with congestive heart failure (CHF) were admitted to the pediatric department of Taleghani General Hospital. During the above period, 192 patients with heart disease were hospitalized at this department and CHF was the cause of admission in 59.4% of them. Congenital heart disease (CHO) w...
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background: heart failure is one of the chronic heart diseases and a debilitating condition of increased prevalence in the elderly. one of the important and non‑pharmacological strategies for improving clinical outcomes in these patients is promotion of the self‑care. background and social environment in which a patient is trying to control his disease is an important factor in the self‑care. t...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2000
ISSN: 0735-1097
DOI: 10.1016/s0735-1097(99)00565-3